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conan install msys2/20210105@ --profile=C:\J\w\BuildSingleReference@3/10088/ee282ff5-9f49-4170-9e79-520a59780b20/profile.txt --build=msys2
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Configuration:
[settings]
arch=x86_64
arch_build=x86_64
build_type=Release
compiler=Visual Studio
compiler.runtime=MT
compiler.version=14
os=Windows
os_build=Windows
[options]
[build_requires]
[env]

msys2/20210105: Forced build from source
Installing package: msys2/20210105
Requirements
    msys2/20210105 from local cache - Cache
Packages
    msys2/20210105:eee3fba89db6d777329de604625af8c30d46f080 - Build

Installing (downloading, building) binaries...
ERROR: C:\J\w\BuildSingleReference@3\.conan\data\msys2\20210105\_\_\package\eee3fba89db6d777329de604625af8c30d46f080

Folder: Cannot change permissions for C:\J\w\BuildSingleReference@3/s\cc3cf1\1\bin\msys64\usr\bin\dirmngr.exe! Exception info: (<class 'PermissionError'>, PermissionError(13, 'Access is denied'), <traceback object at 0x000002605590CE08>)
Couldn't remove folder, might be busy or open
Close any app using it, and retry